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What’re you doing in that car, Beagle? Puppies can’t drive! You know what else puppies can’t do? Accurately predict the toxicity of pharmaceuticals or industrial chemicals in humans. 95% of drugs passed by animal tests are immediately discarded as useless or dangerous to humans. For example, the cardiovascular drugs encainide and flecainide were tested on dogs, deemed to be safe, and then pulled off the market when they killed an estimated 3,000 Americans.